In addition to important nutritional benefits, CitraNatal® ingredients offer comfort, safety, and tolerability.
CitraNatal® products contain calcium citrate, an excellent source of calcium that provides unsurpassed solubility and bioavailability.1 Many other prenatal supplements contain calcium carbonate, which reacts with stomach acid and releases CO2 that can cause gas and bloating.
* Pressure of 500 mg calcium carbonate and 500 mg calcium citrate measured over 4 hours in a sealed flask at a constant temperature of 37° C.
The carbonyl iron included in CitraNatal® products is absorbed in sync with your patient's system. The resulting gentle absorption explains why carbonyl iron is safer and less toxic than other iron products, with equal efficacy.3,4
- Particulate carbonyl iron is converted to soluble ionized iron at a rate determined by the rate of gastric acid production.
- Uptake by intestinal mucosa, absorption, and internal distribution are similar to equivalent doses of ferrous iron salts.
- More "prolonged" absorption of carbonyl iron contrasts with "the larger initial bolus of absorption" with ferrous ammonium sulfate.
CitraNatal® products also include Vitamin C to enhance iron absorption, as well as a gentle stool softener to ease constipation sometimes associated with iron supplementation and pregnancy.
- Heller HJ, Greer LG, Haynes SD, Poindexter JR, Pak CY. Pharmacokinetic and pharmacodynamic comparison of two calcium supplements in postmenopausal women. J Clin Pharmacol. 2000 Nov;40(11):1237-44.
- Data on file. Mission Pharmacal Company.
- Gordeuk VR, Brittenham GM, Hughes M, Keating LJ, Opplt JJ. High-dose carbonyl iron for iron deficiency anemia: a randomized double-blind trial. Am J Clin Nutr. 1987 Dec;46(6):1029-34.
- Huebers HA, Brittenham GM, Csiba E, Finch CA. Absorption of carbonyl iron. J Lab Clin Med. 1986 Nov;108(5):473-8.
More than 500,000 babies are born too soon each year. Some are so small they struggle to survive. This year, Mission Pharmacal is joining forces with the March of Dimes* as a National Corporate Sponsor to help raise awareness about the growing crisis of premature birth. To learn more and help us fight prematurity, click on the links below. For more than 60 years, Mission Pharmacal has been committed to providing products for healthy women and healthy babies.
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