In addition to important nutritional benefits, CitraNatal® ingredients offer comfort, safety, and tolerability.
CitraNatal® products contain calcium citrate, an excellent source of calcium that provides unsurpassed solubility and bioavailability.1 Many other prenatal supplements contain calcium carbonate, which reacts with stomach acid and releases CO2 that can cause gas and bloating.
* Pressure of 500 mg calcium carbonate and 500 mg calcium citrate measured over 4 hours in a sealed flask at a constant temperature of 37° C.
The carbonyl iron included in CitraNatal® products is absorbed in sync with your patient's system. The resulting gentle absorption explains why carbonyl iron is safer and less toxic than other iron products, with equal efficacy.3,4
- Particulate carbonyl iron is converted to soluble ionized iron at a rate determined by the rate of gastric acid production.
- Uptake by intestinal mucosa, absorption, and internal distribution are similar to equivalent doses of ferrous iron salts.
- More "prolonged" absorption of carbonyl iron contrasts with "the larger initial bolus of absorption" with ferrous ammonium sulfate.
CitraNatal® products also include Vitamin C to enhance iron absorption, as well as a gentle stool softener to ease constipation sometimes associated with iron supplementation and pregnancy.
WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. KEEP THIS PRODUCT OUT OF THE REACH OF CHILDREN. In case of accidental overdose, call a doctor or poison control center immediately.
If you are pregnant, may become pregnant, or recently gave birth, CitraNatal® ® prescription multivitamins are designed to improve your nutritional health. Be sure to talk with your physician or healthcare practitioner prior to starting any prescription prenatal vitamin regimen.
Important Safety Information
All CitraNatal® products contain Folic acid, which has been shown to reduce the risk of neural tube defects. Some patients taking Folic acid have reported allergic reactions. Talk to your doctor before taking CitraNatal® if you have a known sensitivity to any of its ingredients.
CitraNatal® products are not for everyone. If you have certain types of anemia (pernicious anemia or other megaloblastic anemias) and you are vitamin B12 deficient, Folic acid alone is not enough to treat your condition. Doses of more than 0.1 mg Folic acid per day can hide the symptoms of these anemias, making them difficult to diagnose. Consult with your doctor to find the treatment that is right for you.
Certain CitraNatal® products contain an all-natural, plant-based form of DHA, an omega-3 fatty acid that is found in the brain and eye. You should exercise caution to ensure that your prescribed dosage does not exceed 1 gram (1000 mg) per day. Taking more than 3 grams of omega-3 fatty acids per day has been shown to have antithrombotic effects, including an increased bleeding time and reduced clotting ratio (INR). Inform your doctor and avoid taking omega-3 fatty acids if you are currently taking anticoagulants (blood thinners) or if you have an inherited or acquired tendency to bleed.
CitraNatal® products include iron. Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under six. Always keep CitraNatal® products and other medications out of reach of children, and in case of accidental overdose, call a doctor or poison control center immediately.
To report negative side effects, contact Mission Pharmacal Company at 1-800-298-1087 or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
- Heller HJ, Greer LG, Haynes SD, Poindexter JR, Pak CY. Pharmacokinetic and pharmacodynamic comparison of two calcium supplements in postmenopausal women. J Clin Pharmacol. 2000 Nov;40(11):1237-44.
- Data on file. Mission Pharmacal Company.
- Gordeuk VR, Brittenham GM, Hughes M, Keating LJ, Opplt JJ. High-dose carbonyl iron for iron deficiency anemia: a randomized double-blind trial. Am J Clin Nutr. 1987 Dec;46(6):1029-34.
- Huebers HA, Brittenham GM, Csiba E, Finch CA. Absorption of carbonyl iron. J Lab Clin Med. 1986 Nov;108(5):473-8.
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